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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5e08ff74c4d18dbf6a7a8f85dee44e3f954487a58c11eda6673a229bea741c' 
  AND token = '6YkkxvpGav+a9qPIDbN5htzgUJjyazgzyat/3nknvw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}