SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    446036, 458366, 401320, 404458, 424315, 
    433313, 419977, 421981, 416661, 445782, 
    415839, 451947
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00095

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost": 0.050171963,
    "nested_loop": [
      {
        "table": {
          "table_name": "cscart_product_prices",
          "access_type": "range",
          "possible_keys": [
            "usergroup",
            "product_id",
            "lower_limit",
            "usergroup_id"
          ],
          "key": "usergroup",
          "key_length": "9",
          "used_key_parts": ["product_id", "usergroup_id", "lower_limit"],
          "loops": 1,
          "rows": 24,
          "cost": 0.04252208,
          "filtered": 50,
          "attached_condition": "cscart_product_prices.lower_limit = 1 and cscart_product_prices.product_id in (446036,458366,401320,404458,424315,433313,419977,421981,416661,445782,415839,451947) and cscart_product_prices.usergroup_id in (0,1)"
        }
      }
    ]
  }
}

Result

product_id price
401320 391.66000000
404458 939.75000000
415839 1940.89000000
416661 1107.34000000
419977 408.20000000
421981 138.04000000
424315 152.11000000
433313 949.50000000
445782 1374.96000000
446036 337.39000000
451947 367.28000000
458366 1701.87000000