SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    451189, 419036, 447640, 448015, 405135, 
    412255, 421594, 426721, 439588, 403510, 
    454572, 420094
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost": 0.050171963,
    "nested_loop": [
      {
        "table": {
          "table_name": "cscart_product_prices",
          "access_type": "range",
          "possible_keys": [
            "usergroup",
            "product_id",
            "lower_limit",
            "usergroup_id"
          ],
          "key": "usergroup",
          "key_length": "9",
          "used_key_parts": ["product_id", "usergroup_id", "lower_limit"],
          "loops": 1,
          "rows": 24,
          "cost": 0.04252208,
          "filtered": 50,
          "attached_condition": "cscart_product_prices.lower_limit = 1 and cscart_product_prices.product_id in (451189,419036,447640,448015,405135,412255,421594,426721,439588,403510,454572,420094) and cscart_product_prices.usergroup_id in (0,1)"
        }
      }
    ]
  }
}

Result

product_id price
403510 1829.39000000
405135 711.40000000
412255 1355.73000000
419036 1259.93000000
420094 884.08000000
421594 330.33000000
426721 1414.13000000
439588 1125.18000000
447640 1296.20000000
448015 1236.20000000
451189 193.15000000
454572 51.30000000